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ripekg:work/10.1097%2Fj.pain.0000000000003503

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ripekg:study-design-evidence/RIPEAD14B78663E061951 ripe:concerns ripekg:work/10.1097%2Fj.pain.0000000000003503Human cold pain: a randomized crossover trial
ripekg:work/10.1097%2Fj.pain.0000000000003503Human cold pain: a randomized crossover trial prism:doi 10.1097/j.pain.0000000000003503
ripekg:work/10.1097%2Fj.pain.0000000000003503Human cold pain: a randomized crossover trial dcterms:creator ripekg:author/RIPEAU01C36AF55A189C4BFarzin Shahi
ripekg:work/10.1097%2Fj.pain.0000000000003503Human cold pain: a randomized crossover trial dcterms:creator ripekg:author/RIPEAU1FBC390D6F1C6824Manuel Zauner
ripekg:work/10.1097%2Fj.pain.0000000000003503Human cold pain: a randomized crossover trial dcterms:creator ripekg:author/RIPEAU7FE17A46DC388B98Cosmin Ciotu
ripekg:work/10.1097%2Fj.pain.0000000000003503Human cold pain: a randomized crossover trial dcterms:creator ripekg:author/RIPEAU827D901D24FD0106Sabine Sator
ripekg:work/10.1097%2Fj.pain.0000000000003503Human cold pain: a randomized crossover trial dcterms:creator ripekg:author/RIPEAUB90C4CA36166E1E0Stefan Heber
ripekg:work/10.1097%2Fj.pain.0000000000003503Human cold pain: a randomized crossover trial dcterms:creator ripekg:author/RIPEAUDEF0A657DC3CBCAAMichael Fischer
ripekg:work/10.1097%2Fj.pain.0000000000003503Human cold pain: a randomized crossover trial dcterms:creator ripekg:author/RIPEAUE726A86B7C2835A7Felix Resch
ripekg:work/10.1097%2Fj.pain.0000000000003503Human cold pain: a randomized crossover trial dcterms:creator ripekg:author/RIPEAUECABE4F9128B9DC5Andreas Gleiss
ripekg:work/10.1097%2Fj.pain.0000000000003503Human cold pain: a randomized crossover trial dcterms:title Human cold pain: a randomized crossover trial
ripekg:work/10.1097%2Fj.pain.0000000000003503Human cold pain: a randomized crossover trial http://purl.org/spar/cito/cites ripekg:work/RIPEW0009C6976A21ED29TRPA1 antagonist LY3526318 inhibits the cinnamaldehydeevoked dermal blood flow increase: translational proof of pharmacology
ripekg:work/10.1097%2Fj.pain.0000000000003503Human cold pain: a randomized crossover trial http://purl.org/spar/cito/cites ripekg:work/RIPEW07E320C1115446BBA phase 1, randomized, double-blind, placebo-controlled, crossover study to evaluate the pharmacodynamic effects of VX-150, a highly selective NaV1.8 inhibitor, in healthy male adults
ripekg:work/10.1097%2Fj.pain.0000000000003503Human cold pain: a randomized crossover trial http://purl.org/spar/cito/cites ripekg:work/RIPEW08C527CB73210A45Fifteen years of Na(V) 1.7 channels as an analgesic target: why has excellent in vitro pharmacology not translated into in vivo analgesic efficacy?
ripekg:work/10.1097%2Fj.pain.0000000000003503Human cold pain: a randomized crossover trial http://purl.org/spar/cito/cites ripekg:work/RIPEW0E27814C6FD96D8CAcute cold hypersensitivity characteristically induced by oxaliplatin is caused by the enhanced responsiveness of TRPA1 in mice
ripekg:work/10.1097%2Fj.pain.0000000000003503Human cold pain: a randomized crossover trial http://purl.org/spar/cito/cites ripekg:work/RIPEW1A107966A97923C6Transient receptor potential ankyrin 1 channel: an evolutionarily tuned thermosensor
ripekg:work/10.1097%2Fj.pain.0000000000003503Human cold pain: a randomized crossover trial http://purl.org/spar/cito/cites ripekg:work/RIPEW2BACB2F9BE41725CMorphofunctional characterisation of axonal damage in different rat models of chemotherapy-induced peripheral neurotoxicity: the role of nerve excitability testing
ripekg:work/10.1097%2Fj.pain.0000000000003503Human cold pain: a randomized crossover trial http://purl.org/spar/cito/cites ripekg:work/RIPEW2C3B468D82289C53A sensory-labeled line for cold: TRPM8-expressing sensory neurons define the cellular basis for cold, cold pain, and cooling-mediated analgesia
ripekg:work/10.1097%2Fj.pain.0000000000003503Human cold pain: a randomized crossover trial http://purl.org/spar/cito/cites ripekg:work/RIPEW2DDB32946F4B2721Effects of temperature on slow and fast inactivation of rat skeletal muscle Na(1) channels
ripekg:work/10.1097%2Fj.pain.0000000000003503Human cold pain: a randomized crossover trial http://purl.org/spar/cito/cites ripekg:work/RIPEW34CE92A6F5899220TRP ion channels in thermosensation, thermoregulation and metabolism
ripekg:work/10.1097%2Fj.pain.0000000000003503Human cold pain: a randomized crossover trial http://purl.org/spar/cito/cites ripekg:work/RIPEW38832420B6D677B4The role of TRPA1 channels in thermosensation
ripekg:work/10.1097%2Fj.pain.0000000000003503Human cold pain: a randomized crossover trial http://purl.org/spar/cito/cites ripekg:work/RIPEW3B633E13E6CC5B44Human pharmacological approaches to TRP-ion-channel-based analgesic drug development
ripekg:work/10.1097%2Fj.pain.0000000000003503Human cold pain: a randomized crossover trial http://purl.org/spar/cito/cites ripekg:work/RIPEW3CC234803038FD5ERQ-00434739, a novel TRPM8 antagonist, inhibits prostaglandin E2-induced hyperactivity of the primary bladder afferent nerves in rats
ripekg:work/10.1097%2Fj.pain.0000000000003503Human cold pain: a randomized crossover trial http://purl.org/spar/cito/cites ripekg:work/RIPEW3D86EEDF714EA68DEpidermal expression of human TRPM8, but not of TRPA1 ion channels, is associated with sensory responses to local skin cooling
ripekg:work/10.1097%2Fj.pain.0000000000003503Human cold pain: a randomized crossover trial http://purl.org/spar/cito/cites ripekg:work/RIPEW42DECCAE43D3AB82TRPA1 sensitization produces hyperalgesia to heat but not to cold stimuli in human volunteers
ripekg:work/10.1097%2Fj.pain.0000000000003503Human cold pain: a randomized crossover trial http://purl.org/spar/cito/cites ripekg:work/RIPEW567BFE9A6FD0AB5ESynthetic interstitial fluid for isolated mammalian tissue
ripekg:work/10.1097%2Fj.pain.0000000000003503Human cold pain: a randomized crossover trial http://purl.org/spar/cito/cites ripekg:work/RIPEW5AA1D7DF7C030A0BAgonist-induced sensitisation of the irritant receptor ion channel TRPA1
ripekg:work/10.1097%2Fj.pain.0000000000003503Human cold pain: a randomized crossover trial http://purl.org/spar/cito/cites ripekg:work/RIPEW5BCC49E512321A4FTRPA1 channels: molecular sentinels of cellular stress and tissue damage
ripekg:work/10.1097%2Fj.pain.0000000000003503Human cold pain: a randomized crossover trial http://purl.org/spar/cito/cites ripekg:work/RIPEW626D1728318EA9C9Species-specific temperature sensitivity of TRPA1
ripekg:work/10.1097%2Fj.pain.0000000000003503Human cold pain: a randomized crossover trial http://purl.org/spar/cito/cites ripekg:work/RIPEW649824F5817A8A35Human heat sensation: a randomized crossover trial
ripekg:work/10.1097%2Fj.pain.0000000000003503Human cold pain: a randomized crossover trial http://purl.org/spar/cito/cites ripekg:work/RIPEW67E557A352C8F996Pharmacological reversal of a pain phenotype in iPSCderived sensory neurons and patients with inherited erythromelalgia
ripekg:work/10.1097%2Fj.pain.0000000000003503Human cold pain: a randomized crossover trial http://purl.org/spar/cito/cites ripekg:work/RIPEW69CE9E9BD6C58E45double-blind, placebocontrolled trial of ISC 17536, an oral inhibitor of transient receptor potential ankyrin 1, in patients with painful diabetic peripheral neuropathy: impact of preserved small nerve fiber function
ripekg:work/10.1097%2Fj.pain.0000000000003503Human cold pain: a randomized crossover trial http://purl.org/spar/cito/cites ripekg:work/RIPEW6A25451D98356390Nav1.7 is required for normal C-low threshold mechanoreceptor function in humans and mice
ripekg:work/10.1097%2Fj.pain.0000000000003503Human cold pain: a randomized crossover trial http://purl.org/spar/cito/cites ripekg:work/RIPEW6AE75B3857F94EE2Ionic mechanisms of spinal neuronal cold hypersensitivity in ciguatera
ripekg:work/10.1097%2Fj.pain.0000000000003503Human cold pain: a randomized crossover trial http://purl.org/spar/cito/cites ripekg:work/RIPEW6E59B42105369312Distinct Nav1.7-dependent pain sensations require different sets of sensory and sympathetic neurons
ripekg:work/10.1097%2Fj.pain.0000000000003503Human cold pain: a randomized crossover trial http://purl.org/spar/cito/cites ripekg:work/RIPEW6F1D99718B4C365DHuman TRPA1 is a heat sensor displaying intrinsic U-shaped thermosensitivity
ripekg:work/10.1097%2Fj.pain.0000000000003503Human cold pain: a randomized crossover trial http://purl.org/spar/cito/cites ripekg:work/RIPEW6FD3EF0DE99B2CCAGenetic predictors for acute experimental cold and heat pain sensitivity in humans
ripekg:work/10.1097%2Fj.pain.0000000000003503Human cold pain: a randomized crossover trial http://purl.org/spar/cito/cites ripekg:work/RIPEW74C066BADBD4DA8FA human TRPA1-specific pain model
ripekg:work/10.1097%2Fj.pain.0000000000003503Human cold pain: a randomized crossover trial http://purl.org/spar/cito/cites ripekg:work/RIPEW7ACAE64751401EBDTRPA1 and TRPM8 activation in humans: effects of cinnamaldehyde and menthol
ripekg:work/10.1097%2Fj.pain.0000000000003503Human cold pain: a randomized crossover trial http://purl.org/spar/cito/cites ripekg:work/RIPEW7B78D5374175F736The revised International Association for the Study of Pain definition of pain: concepts, challenges, and compromises
ripekg:work/10.1097%2Fj.pain.0000000000003503Human cold pain: a randomized crossover trial http://purl.org/spar/cito/cites ripekg:work/RIPEW7F60871721D4FD8CTemperature sensitivity of the body surface over the life span
ripekg:work/10.1097%2Fj.pain.0000000000003503Human cold pain: a randomized crossover trial http://purl.org/spar/cito/cites ripekg:work/RIPEW81E01AFD2A9493D1TRPA1 contributes to cold hypersensitivity
ripekg:work/10.1097%2Fj.pain.0000000000003503Human cold pain: a randomized crossover trial http://purl.org/spar/cito/cites ripekg:work/RIPEW9316596F47413C55Cold sensing by Na(V)1.8-positive and Na(V)1.8-negative sensory neurons
ripekg:work/10.1097%2Fj.pain.0000000000003503Human cold pain: a randomized crossover trial http://purl.org/spar/cito/cites ripekg:work/RIPEW9347690807A4A7BFCapsaicin or menthol sensitization induces quantitative but no qualitative changes to thermal and mechanical pain thresholds
ripekg:work/10.1097%2Fj.pain.0000000000003503Human cold pain: a randomized crossover trial http://purl.org/spar/cito/cites ripekg:work/RIPEW9CB7C87ADDB76046Nav1.7 and other voltage-gated sodium channels as drug targets for pain relief
ripekg:work/10.1097%2Fj.pain.0000000000003503Human cold pain: a randomized crossover trial http://purl.org/spar/cito/cites ripekg:work/RIPEWAC863FE7EBD68312Cutaneous distribution and localization of dyes affected by vehicles all with different lipophilicity
ripekg:work/10.1097%2Fj.pain.0000000000003503Human cold pain: a randomized crossover trial http://purl.org/spar/cito/cites ripekg:work/RIPEWAE0F478ADE42F609Multimodal distribution of human cold pain thresholds
ripekg:work/10.1097%2Fj.pain.0000000000003503Human cold pain: a randomized crossover trial http://purl.org/spar/cito/cites ripekg:work/RIPEWB0C0485606D254EAOxaliplatin-and docetaxelinduced polyneuropathy: clinical and neurophysiological characteristics
ripekg:work/10.1097%2Fj.pain.0000000000003503Human cold pain: a randomized crossover trial http://purl.org/spar/cito/cites ripekg:work/RIPEWB6B096E061BD9A69Cold temperature encoding by cutaneous TRPA1 and TRPM8-carrying fibers in the mouse
ripekg:work/10.1097%2Fj.pain.0000000000003503Human cold pain: a randomized crossover trial http://purl.org/spar/cito/cites ripekg:work/RIPEWBC180236B49155DBSubtype-selective small molecule inhibitors reveal a fundamental role for Nav1.7 in nociceptor electrogenesis, axonal conduction and presynaptic release
ripekg:work/10.1097%2Fj.pain.0000000000003503Human cold pain: a randomized crossover trial http://purl.org/spar/cito/cites ripekg:work/RIPEWC4E328823AB02575The discovery and optimization of benzimidazoles as selective Na(V)1.8 blockers for the treatment of pain
ripekg:work/10.1097%2Fj.pain.0000000000003503Human cold pain: a randomized crossover trial http://purl.org/spar/cito/cites ripekg:work/RIPEWC905D2AAC140B6C0Arendt-Nielsen L. Somatosensory and vasomotor manifestations of individual and combined stimulation of TRPM8 and TRPA1 using topical L-menthol and trans-cinnamaldehyde in healthy volunteers
ripekg:work/10.1097%2Fj.pain.0000000000003503Human cold pain: a randomized crossover trial http://purl.org/spar/cito/cites ripekg:work/RIPEWCD17E7052CB65A61Reference data for quantitative sensory testing (QST): refined stratification for age and a novel method for statistical comparison of group data
ripekg:work/10.1097%2Fj.pain.0000000000003503Human cold pain: a randomized crossover trial http://purl.org/spar/cito/cites ripekg:work/RIPEWD1EC3197A30E1A55The physiological function of different voltagegated sodium channels in pain
ripekg:work/10.1097%2Fj.pain.0000000000003503Human cold pain: a randomized crossover trial http://purl.org/spar/cito/cites ripekg:work/RIPEWD61DE02B3509854CThe role of cold-sensitive ion channels in peripheral thermosensation
ripekg:work/10.1097%2Fj.pain.0000000000003503Human cold pain: a randomized crossover trial http://purl.org/spar/cito/cites ripekg:work/RIPEWDAD389C6623527F6Defining the functional role of Na(V)1.7 in human nociception
ripekg:work/10.1097%2Fj.pain.0000000000003503Human cold pain: a randomized crossover trial http://purl.org/spar/cito/cites ripekg:work/RIPEWDEC095D343EDE588Lack of detection of the analgesic properties of PF-05089771, a selective Na(v) 1.7 inhibitor, using a battery of pain models in healthy subjects
ripekg:work/10.1097%2Fj.pain.0000000000003503Human cold pain: a randomized crossover trial http://purl.org/spar/cito/cites ripekg:work/RIPEWE80C5C57D84E86BATransient receptor potential TRPA1 channel desensitization in sensory neurons is agonist dependent and regulated by TRPV1-directed internalization
ripekg:work/10.1097%2Fj.pain.0000000000003503Human cold pain: a randomized crossover trial http://purl.org/spar/cito/cites ripekg:work/RIPEWEA1639375EE63DEDInhibition of TRPM8 channels reduces pain in the cold pressor test in humans
ripekg:work/10.1097%2Fj.pain.0000000000003503Human cold pain: a randomized crossover trial http://purl.org/spar/cito/cites ripekg:work/RIPEWEB560CFEF798614EHigh-density thermal sensitivity maps of the human body
ripekg:work/10.1097%2Fj.pain.0000000000003503Human cold pain: a randomized crossover trial http://purl.org/spar/cito/cites ripekg:work/RIPEWEF2A967EF9696FD0Quantitative sensory testing in the German Research Network on Neuropathic Pain (DFNS): somatosensory abnormalities in 1236 patients with different neuropathic pain syndromes
ripekg:work/10.1097%2Fj.pain.0000000000003503Human cold pain: a randomized crossover trial http://purl.org/spar/cito/cites ripekg:work/RIPEWF5D518F32BF29833Sensory neuron sodium channel Nav1.8 is essential for pain at low temperatures
ripekg:work/10.1097%2Fj.pain.0000000000003503Human cold pain: a randomized crossover trial http://purl.org/spar/cito/cites ripekg:work/RIPEWFFE3AF8E727B0083TRPV1 antagonist BCTC inhibits pH 6.0-induced pain in human skin
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