The effects of spirulina intake on clinical and metabolic parameters in Alzheimer's disease: A randomized, double‐blind, controlled trial
Assessed by RV019 · Evidence Synthesis Methdos Lead
Assessed on 8 Mar 2026
OverallReviewer's overall integrity assessment, derived from all research questions Serious concerns
DOI 10.1002/ptr.7791 (opens in new tab)
Resource ripekg:research-integrity-assessment/RIPEAD590A93EC19D8A75
5 Research Questions · 28 Evidence Items
Q1.1 — Does the study have an associated retraction?
Rationale: No rationale provided
Q1.2 — Does the study have an associated expression of concern or other relevant post-publication notice?
Rationale: No rationale provided
Q1.3 — Do other studies by the research team highlight causes for concern?
Rationale: No rationale provided
Supporting Evidence (26)
Retraction NoticeSource: Retraction Watch database
The effects of coenzyme Q10 supplementation on gene expression related to insulin, lipid and inflammation in patients with polycystic ovary syndrome
10.1080/09513590.2024.2334596 (opens in new tab)RetractionWatch ID:Record identifier in the Retraction Watch database 53090
Rationale: Concerns/Issues About Data;Concerns/Issues about Results and/or Conclusions;Investigation by Journal/Publisher;Investigation by Third Party;Objections by Author(s);Unreliable Results and/or Conclusions;Upgrade/Update of Prior Notice(s)
About Authors: Omid Tamtaji, Mehri Jamilian, Mansooreh Samimi, Elmira Akbari, Esmat Aghadavod
Retraction NoticeSource: Retraction Watch database
Probiotic supplementation and the effects on weight loss, glycaemia and lipid profiles in women with polycystic ovary syndrome: a randomized, double-blind, placebo-controlled trial
10.1080/14647273.2024.2373595 (opens in new tab)RetractionWatch ID:Record identifier in the Retraction Watch database 54767
Rationale: Concerns/Issues About Data;Concerns/Issues about Results and/or Conclusions;Concerns/Issues about Referencing/Attributions;Investigation by Journal/Publisher;Investigation by Third Party;Objections by Author(s);Unreliable Results and/or Conclusions;Upgrade/Update of Prior Notice(s)
About Authors: Mohsen Taghizadeh, Zatollah Asemi, Mehri Jamilian, Maryam Tajabadi-Ebrahimi, Maryam Karamali, Mohammad Memarzadeh
Retraction NoticeSource: Retraction Watch database
Effect of daily consumption of probiotic yoghurt on lipid profiles in pregnant women: a randomized controlled clinical trial
10.1080/14767058.2024.2364976 (opens in new tab)RetractionWatch ID:Record identifier in the Retraction Watch database 67044
Rationale: Concerns/Issues About Data;Concerns/Issues about Results and/or Conclusions;Investigation by Journal/Publisher;Investigation by Third Party;Objections by Author(s);Unreliable Results and/or Conclusions;Upgrade/Update of Prior Notice(s)
About Authors: Zatollah Asemi, Ahmad Esmaillzadeh
Q2.2 — Are there concerns relating to the timing or absence of study registration?
Rationale: No rationale provided
Supporting Evidence (2)
Clinical Trial RegistrationSource: Clinical trial registry (e.g. ClinicalTrials.gov, ISRCTN)
Registration ID: IRCT20170612034497N6
Registry: IRCT
Registry Link: https://trialsearch.who.int/Trial2.aspx?TrialID=IRCT20170612034497N6 (opens in new tab)
Registration Date: 4 Dec 2019
Prospective:Whether the trial was registered before participant recruitment began No
Assessment Rationale:How INSPECT-AI determined the prospective registration status by comparing dates Comparison performed at month level. Registration: 2019-12, LLM Recruitment Start: 2019-07. Deemed retrospective at month level.
Study Design EvidenceDates and timelines extracted by INSPECT-AI from the publication text
Recruitment Start: 07-2019
Recruitment Start Rationale:INSPECT-AI's reasoning for how it identified the recruitment start date Methods: 'between July 2019 and March 2020 (recruitment date: July 2019 until December 2019 and intervention date December 2019 until March 2020)'
Recruitment End: 12-2019
Recruitment End Rationale:INSPECT-AI's reasoning for how it identified the recruitment end date Methods: 'between July 2019 and March 2020 (recruitment date: July 2019 until December 2019 and intervention date December 2019 until March 2020)'
Study End: 03-2020
Study End Rationale:INSPECT-AI's reasoning for how it identified the study end date Methods: 'between July 2019 and March 2020 (recruitment date: July 2019 until December 2019 and intervention date December 2019 until March 2020)'
Overall — What is the overall integrity assessment of the study?
Rationale: No rationale provided