Pelvic Lymph Node Dissection in Prostate Cancer: Update from a Randomized Clinical Trial of Limited Versus Extended Dissection
Assessed by RV011 · Statistician
Assessed on 17 Nov 2025
OverallReviewer's overall integrity assessment, derived from all research questions No concerns
DOI 10.1016/j.eururo.2024.10.006 (opens in new tab)
Resource ripekg:research-integrity-assessment/RIPEAA29E3E0362BE3ECB
5 Research Questions · 2 Evidence Items
Q1.1 — Does the study have an associated retraction?
Rationale: I agree.
Q1.2 — Does the study have an associated expression of concern or other relevant post-publication notice?
Rationale: No concerns that I am aware of.
Q1.3 — Do other studies by the research team highlight causes for concern?
Rationale: I agree.
Q2.2 — Are there concerns relating to the timing or absence of study registration?
Rationale: It seemed clear to me that the study was registered before the first participant was recruited.
Supporting Evidence (2)
Clinical Trial RegistrationSource: Clinical trial registry (e.g. ClinicalTrials.gov, ISRCTN)
Registration ID: NCT01407263
Registry: ClinicalTrials.gov
Registry Link: https://clinicaltrials.gov/study/NCT01407263 (opens in new tab)
Registration Date: 29-07-2011
Prospective:Whether the trial was registered before participant recruitment began Yes
Assessment Rationale:How INSPECT-AI determined the prospective registration status by comparing dates Comparison performed at month level. Registration: 2011-07, LLM Recruitment Start: 2011-10. Deemed prospective at month level.
Study Design EvidenceDates and timelines extracted by INSPECT-AI from the publication text
Recruitment Start: 10-2011
Recruitment Start Rationale:INSPECT-AI's reasoning for how it identified the recruitment start date Methods: 'Between October 2011 and March 2017, 1432 patients undergoing radical prostatectomy were enrolled at a single center.' so recruitment start is October 2011
Recruitment End: 03-2017
Recruitment End Rationale:INSPECT-AI's reasoning for how it identified the recruitment end date Methods: 'Between October 2011 and March 2017, 1432 patients undergoing radical prostatectomy were enrolled at a single center.' so recruitment finish is March 2017
Study End: N/A
Study End Rationale:INSPECT-AI's reasoning for how it identified the study end date No explicit study end date found.
Overall — What is the overall integrity assessment of the study?
Rationale: None of the checks caused any concern and I am not aware of any other concerns which have been raised regarding this study.