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Evidence that a novel transdiagnostic eating disorder treatment reduces reward region response to the thin beauty ideal and high-calorie binge foods

Assessed by RV008 · PhD Candidate

Assessed on 7 Nov 2025

OverallReviewer's overall integrity assessment, derived from all research questions Serious concerns

DOI 10.1017/s0033291721004049 (opens in new tab)

Resource ripekg:research-integrity-assessment/RIPEA7D7312C6B4E5005A

5 Research Questions · 2 Evidence Items

Q1.1 — Does the study have an associated retraction?

Automated Assessment:Assessment produced by the automated systemNo
Human Assessment:Assessment by a domain expert reviewer, informed by AI resultsNo

Rationale: No retractions found on the publisher's website.

Q1.2 — Does the study have an associated expression of concern or other relevant post-publication notice?

Automated Assessment:Assessment produced by the automated systemNo
Human Assessment:Assessment by a domain expert reviewer, informed by AI resultsNo

Rationale: No comments found when searching on PubPeer.

Q1.3 — Do other studies by the research team highlight causes for concern?

Automated Assessment:Assessment produced by the automated systemNo
Human Assessment:Assessment by a domain expert reviewer, informed by AI resultsNo

Rationale: No rationale provided

Q2.2 — Are there concerns relating to the timing or absence of study registration?

Automated Assessment:Assessment produced by the automated systemUnclear
Human Assessment:Assessment by a domain expert reviewer, informed by AI resultsYes

Rationale: No trial registration was mentioned in the article. Is it safe to assume the trial isn't registered?

Supporting Evidence (2)

Clinical Trial RegistrationSource: Clinical trial registry (e.g. ClinicalTrials.gov, ISRCTN)

No trial registration found

Assessment Rationale:How INSPECT-AI determined the prospective registration status by comparing dates LLM-extracted recruitment start date (normalized_date) is missing or empty.

Study Design EvidenceDates and timelines extracted by INSPECT-AI from the publication text

Recruitment Start: N/A

Recruitment Start Rationale:INSPECT-AI's reasoning for how it identified the recruitment start date No recruitment start date found.

Recruitment End: N/A

Recruitment End Rationale:INSPECT-AI's reasoning for how it identified the recruitment end date No recruitment end date found.

Study End: N/A

Study End Rationale:INSPECT-AI's reasoning for how it identified the study end date No study end date found.

Overall — What is the overall integrity assessment of the study?

Automated Assessment:Assessment produced by the automated systemN/A
Human Assessment:Assessment by a domain expert reviewer, informed by AI resultsSerious concerns

Rationale: The trial passes all checks until the registration. There is no trial registration mentioned in the article which is driving the overall judgement to have serious concerns.

Assessment: Evidence that a novel transdiagnostic eating disorder treatment reduces reward region response to the thin beauty ideal and high-calorie binge foods | RIPE Knowledge Graph