One Full or Two Fractional Doses of Inactivated Poliovirus Vaccine for Catch-up Vaccination in Older Infants: A Randomized Clinical Trial in Bangladesh

Assessed by RV006 · Research Assistant/Biostatistician

Assessed on 4 Nov 2025

OverallReviewer's overall integrity assessment, derived from all research questions Some concerns

DOI 10.1093/infdis/jiac205 (opens in new tab)

Resource ripekg:research-integrity-assessment/RIPEA77544FAAC5874F79

5 Research Questions · 2 Evidence Items

Q1.1 — Does the study have an associated retraction?

Automated Assessment:Assessment produced by the automated systemNo

Human Assessment:Assessment by a domain expert reviewer, informed by AI resultsNo

Rationale: No rationale provided

Q1.2 — Does the study have an associated expression of concern or other relevant post-publication notice?

Automated Assessment:Assessment produced by the automated systemNo

Human Assessment:Assessment by a domain expert reviewer, informed by AI resultsNo

Rationale: No rationale provided

Q1.3 — Do other studies by the research team highlight causes for concern?

Automated Assessment:Assessment produced by the automated systemNo

Human Assessment:Assessment by a domain expert reviewer, informed by AI resultsNo

Rationale: No rationale provided

Q2.2 — Are there concerns relating to the timing or absence of study registration?

Automated Assessment:Assessment produced by the automated systemYes

Human Assessment:Assessment by a domain expert reviewer, informed by AI resultsYes

Rationale: No rationale provided

Supporting Evidence (2)

Clinical Trial RegistrationSource: Clinical trial registry (e.g. ClinicalTrials.gov, ISRCTN)

Registration ID: NCT03890497

Registry: ClinicalTrials.gov

Registry Link: https://clinicaltrials.gov/study/NCT03890497 (opens in new tab)

Registration Date: 24-03-2019

Prospective:Whether the trial was registered before participant recruitment began No

Assessment Rationale:How INSPECT-AI determined the prospective registration status by comparing dates Registration date is after LLM recruitment start date.

Study Design EvidenceDates and timelines extracted by INSPECT-AI from the publication text

Recruitment Start: 28-09-2018

Recruitment Start Rationale:INSPECT-AI's reasoning for how it identified the recruitment start date Results: 'Between 28 September 2018 and 26 June 2019, parents of 380 potentially eligible children were approached for study participation...'

Recruitment End: 26-06-2019

Recruitment End Rationale:INSPECT-AI's reasoning for how it identified the recruitment end date Results: 'Between 28 September 2018 and 26 June 2019, parents of 380 potentially eligible children were approached for study participation...'

Study End: 26-06-2019

Study End Rationale:INSPECT-AI's reasoning for how it identified the study end date Results: 'Between 28 September 2018 and 26 June 2019, parents of 380 potentially eligible children were approached for study participation...'; using the end of recruitment as the study end date because no explicit study end date was found.

Overall — What is the overall integrity assessment of the study?

Automated Assessment:Assessment produced by the automated systemN/A

Human Assessment:Assessment by a domain expert reviewer, informed by AI resultsSome concerns

Rationale: 6 months retrospective of the study registration.