Calcium-Vitamin D co-supplementation affects metabolic profiles, but not pregnancy outcomes, in healthy pregnant women

Assessed by RV013 · Clinical Chair in Health Services Research

Assessed on 12 Nov 2025

OverallReviewer's overall integrity assessment, derived from all research questions Serious concerns

DOI 10.4103/2008-7802.177895 (opens in new tab)

Resource ripekg:research-integrity-assessment/RIPEA533765E11F40F1A0

5 Research Questions · 66 Evidence Items

Q1.1 — Does the study have an associated retraction?

Automated Assessment:Assessment produced by the automated systemNo

Human Assessment:Assessment by a domain expert reviewer, informed by AI resultsNo

Rationale: Not retracted on website

Q1.2 — Does the study have an associated expression of concern or other relevant post-publication notice?

Automated Assessment:Assessment produced by the automated systemYes

Human Assessment:Assessment by a domain expert reviewer, informed by AI resultsYes

Rationale: PubPeer comments

Supporting Evidence (1)

PubPeer ThreadSource: PubPeer.com — post-publication peer review comments

https://pubpeer.com/publications/4A221B72BE4B337B4F4DC334578A4D

PubPeer CommentSource: PubPeer.com — a platform for post-publication peer review

Commenter: Andrew GreyDate: 1 May 2021

There are many concerns about the integrity of 172 publications by this research group, including this one. Some of the concerns are published 1. Anaesthesia 2020;75:1683–92, see Supplementary data. This paper is A48 2. Account Res 2020;28:149-61. 3. J Clin Epidemiol 2021;131:22-29. Journals and publishers were notified of these concerns in July 2019. 23 publications have an expression of concern. To our knowledge there has been no public response about any of the concerns. We think these publications are unreliable

Thread: https://pubpeer.com/publications/4A221B72BE4B337B4F4DC334578A4D (opens in new tab)

Q1.3 — Do other studies by the research team highlight causes for concern?

Automated Assessment:Assessment produced by the automated systemYes

Human Assessment:Assessment by a domain expert reviewer, informed by AI resultsYes

Rationale: Plenty of problems with the research team

Supporting Evidence (63)

Retraction NoticeSource: Retraction Watch database

The Effect of Zinc Supplementation on Expressed Levels of Peroxisome Proliferator-Activated Receptor Gamma and Glucose Transporter Type 1 Genes in Newborns of Women with Gestational Diabetes Mellitus

10.1007/s12011-016-0788-y

Journal: Biological Trace Element ResearchPublisher: SpringerDate: 28 Feb 2021

RetractionWatch ID:Record identifier in the Retraction Watch database 28454

Rationale: Concerns/Issues About Data;Investigation by Company/Institution;Updated to Retraction

About Authors: Mehri Jamilian, Mansooreh Samimi, Esmat Aghadavod

Retracts: 10.1007/s12011-016-0788-y

Retraction NoticeSource: Retraction Watch database

Effects of Selenium Supplementation on Gene Expression Levels of Inflammatory Cytokines and Vascular Endothelial Growth Factor in Patients with Gestational Diabetes

10.1007/s12011-017-1045-8

Journal: Biological Trace Element ResearchPublisher: SpringerDate: 28 Feb 2021

RetractionWatch ID:Record identifier in the Retraction Watch database 28465

Rationale: Concerns/Issues About Data;Investigation by Company/Institution

About Authors: Mehri Jamilian, Mansooreh Samimi, Esmat Aghadavod, Faraneh Afshar Ebrahimi

Retracts: 10.1007/s12011-017-1045-8

Retraction NoticeSource: Retraction Watch database

The Effect of Zinc Supplementation on Expressed Levels of Peroxisome Proliferator-Activated Receptor Gamma and Glucose Transporter Type 1 Genes in Newborns of Women with Gestational Diabetes Mellitus

10.1007/s12011-022-03501-2

Journal: Biological Trace Element ResearchPublisher: SpringerDate: 24 Nov 2022

RetractionWatch ID:Record identifier in the Retraction Watch database 40895

Rationale: Concerns/Issues About Data;Concerns/Issues About Image;Concerns/Issues about Referencing/Attributions;Duplication of/in Article;Investigation by Company/Institution;Unreliable Results and/or Conclusions;Upgrade/Update of Prior Notice(s)

About Authors: Mehri Jamilian, Mansooreh Samimi, Esmat Aghadavod

Retracts: 10.1007/s12011-016-0788-y

Q2.2 — Are there concerns relating to the timing or absence of study registration?

Automated Assessment:Assessment produced by the automated systemUnclear

Human Assessment:Assessment by a domain expert reviewer, informed by AI resultsUnclear

Rationale: Agree, no registration details

Supporting Evidence (2)

Clinical Trial RegistrationSource: Clinical trial registry (e.g. ClinicalTrials.gov, ISRCTN)

No trial registration found

Assessment Rationale:How INSPECT-AI determined the prospective registration status by comparing dates Registry registration date (study_first_submit_qc_date) is missing or empty.

Study Design EvidenceDates and timelines extracted by INSPECT-AI from the publication text

Recruitment Start: 03-2012

Recruitment Start Rationale:INSPECT-AI's reasoning for how it identified the recruitment start date Methods: 'The current clinical trial was done in Kashan, Iran, from March 2012'; no specific day found.

Recruitment End: N/A

Recruitment End Rationale:INSPECT-AI's reasoning for how it identified the recruitment end date No explicit recruitment_finish date found.

Study End: 09-2012

Study End Rationale:INSPECT-AI's reasoning for how it identified the study end date Methods: 'The current clinical trial was done in Kashan, Iran, from March 2012 to September 2012'; no specific day found.

Overall — What is the overall integrity assessment of the study?

Automated Assessment:Assessment produced by the automated systemN/A

Human Assessment:Assessment by a domain expert reviewer, informed by AI resultsSerious concerns

Rationale: Serious concerns based on PubPeer and authors' records