Effect of low-dose selenium on thyroid autoimmunity and thyroid function in UK pregnant women with mild-to-moderate iodine deficiency

Assessed by RV018 · Methods Support Unit Manager

Assessed on 4 Mar 2026

OverallReviewer's overall integrity assessment, derived from all research questions Some concerns

DOI 10.1007/s00394-014-0822-9 (opens in new tab)

Resource ripekg:research-integrity-assessment/RIPEA3EDD1540E20C47B1

5 Research Questions · 2 Evidence Items

Q1.1 — Does the study have an associated retraction?

Automated Assessment:Assessment produced by the automated systemNo

Human Assessment:Assessment by a domain expert reviewer, informed by AI resultsNo

Rationale: No rationale provided

Q1.2 — Does the study have an associated expression of concern or other relevant post-publication notice?

Automated Assessment:Assessment produced by the automated systemNo

Human Assessment:Assessment by a domain expert reviewer, informed by AI resultsNo

Rationale: No rationale provided

Q1.3 — Do other studies by the research team highlight causes for concern?

Automated Assessment:Assessment produced by the automated systemNo

Human Assessment:Assessment by a domain expert reviewer, informed by AI resultsNo

Rationale: No rationale provided

Q2.2 — Are there concerns relating to the timing or absence of study registration?

Automated Assessment:Assessment produced by the automated systemUnclear

Human Assessment:Assessment by a domain expert reviewer, informed by AI resultsUnclear

Rationale: No rationale provided

Supporting Evidence (2)

Clinical Trial RegistrationSource: Clinical trial registry (e.g. ClinicalTrials.gov, ISRCTN)

Registration ID: ISRCTN37927591

Registry: ISRCTN

Registry Link: https://trialsearch.who.int/Trial2.aspx?TrialID=ISRCTN37927591 (opens in new tab)

Registration Date: 5 Oct 2013

Prospective:Whether the trial was registered before participant recruitment began No

Assessment Rationale:How INSPECT-AI determined the prospective registration status by comparing dates LLM-extracted recruitment start date (normalized_date) is missing or empty.

Study Design EvidenceDates and timelines extracted by INSPECT-AI from the publication text

Recruitment Start: N/A

Recruitment Start Rationale:INSPECT-AI's reasoning for how it identified the recruitment start date No recruitment start date found in the text.

Recruitment End: N/A

Recruitment End Rationale:INSPECT-AI's reasoning for how it identified the recruitment end date No recruitment finish date found in the text.

Study End: N/A

Study End Rationale:INSPECT-AI's reasoning for how it identified the study end date No study end date found in the text.

Overall — What is the overall integrity assessment of the study?

Automated Assessment:Assessment produced by the automated systemN/A

Human Assessment:Assessment by a domain expert reviewer, informed by AI resultsSome concerns

Rationale: Unclear whether recruitment and study dates matched those reported in the trial registry - no data in paper.