Effect of oral semaglutide on energy intake, appetite, control of eating and gastric emptying in adults living with obesity: A randomized controlled trial

Assessed by RV012 · Lecturer (Teaching & Research)

Assessed on 30 Oct 2025

OverallReviewer's overall integrity assessment, derived from all research questions No concerns

DOI 10.1111/dom.15802 (opens in new tab)

Resource ripekg:research-integrity-assessment/RIPEA312D0E8F4C1164EF

5 Research Questions · 2 Evidence Items

Q1.1 — Does the study have an associated retraction?

Automated Assessment:Assessment produced by the automated systemNo

Human Assessment:Assessment by a domain expert reviewer, informed by AI resultsNo

Rationale: Nothing on the website either

Q1.2 — Does the study have an associated expression of concern or other relevant post-publication notice?

Automated Assessment:Assessment produced by the automated systemNo

Human Assessment:Assessment by a domain expert reviewer, informed by AI resultsNo

Rationale: No concerns, but note it is a recent paper

Q1.3 — Do other studies by the research team highlight causes for concern?

Automated Assessment:Assessment produced by the automated systemNo

Human Assessment:Assessment by a domain expert reviewer, informed by AI resultsNo

Rationale: No concerns

Q2.2 — Are there concerns relating to the timing or absence of study registration?

Automated Assessment:Assessment produced by the automated systemNo

Human Assessment:Assessment by a domain expert reviewer, informed by AI resultsNo

Rationale: No concerns

Supporting Evidence (2)

Clinical Trial RegistrationSource: Clinical trial registry (e.g. ClinicalTrials.gov, ISRCTN)

Registration ID: NCT05236517

Registry: ClinicalTrials.gov

Registry Link: https://clinicaltrials.gov/study/NCT05236517 (opens in new tab)

Registration Date: 04-02-2022

Prospective:Whether the trial was registered before participant recruitment began Yes

Assessment Rationale:How INSPECT-AI determined the prospective registration status by comparing dates Registration date is on or before LLM recruitment start date.

Study Design EvidenceDates and timelines extracted by INSPECT-AI from the publication text

Recruitment Start: 08-02-2022

Recruitment Start Rationale:INSPECT-AI's reasoning for how it identified the recruitment start date Study design: 'from 8 February to 7 November 2022' indicates recruitment started on 08-02-2022.

Recruitment End: N/A

Recruitment End Rationale:INSPECT-AI's reasoning for how it identified the recruitment end date No explicit recruitment_finish date found.

Study End: 07-11-2022

Study End Rationale:INSPECT-AI's reasoning for how it identified the study end date Study design: 'from 8 February to 7 November 2022' indicates study ended on 07-11-2022.

Overall — What is the overall integrity assessment of the study?

Automated Assessment:Assessment produced by the automated systemN/A

Human Assessment:Assessment by a domain expert reviewer, informed by AI resultsNo concerns

Rationale: No concerns