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Calcium plus vitamin D supplementation affects glucose metabolism and lipid concentrations in overweight and obese vitamin D deficient women with polycystic ovary syndrome

Assessed by RV019 · Evidence Synthesis Methdos Lead

Assessed on 8 Mar 2026

OverallReviewer's overall integrity assessment, derived from all research questions Serious concerns

DOI 10.1016/j.clnu.2014.09.015 (opens in new tab)

Resource ripekg:research-integrity-assessment/RIPEA22B2228793442254

5 Research Questions · 66 Evidence Items

Q1.1 — Does the study have an associated retraction?

Automated Assessment:Assessment produced by the automated systemNo
Human Assessment:Assessment by a domain expert reviewer, informed by AI resultsNo

Rationale: No rationale provided

Q1.2 — Does the study have an associated expression of concern or other relevant post-publication notice?

Automated Assessment:Assessment produced by the automated systemYes
Human Assessment:Assessment by a domain expert reviewer, informed by AI resultsYes

Rationale: No rationale provided

Supporting Evidence (2)

PubPeer ThreadSource: PubPeer.com — post-publication peer review comments

https://pubpeer.com/publications/925CE537207BD1E90FE94ACEEF71F0 (opens in new tab)

PubPeer CommentSource: PubPeer.com — a platform for post-publication peer review

Commenter: Andrew GreyDate: 1 Apr 2021

There are many concerns about the integrity of 172 publications by this research group, including this one. Some of the concerns are published 1. Anaesthesia 2020;75:1683–92, see Supplementary data. This paper is A28 2. Account Res 2020;28:149-61. 3. J Clin Epidemiol 2021;131:22-29. Journals and publishers were notified of these concerns in July 2019. 23 publications have an expression of concern. To our knowledge there has been no public response about any of the concerns. We think these publications are unreliable

Thread: https://pubpeer.com/publications/925CE537207BD1E90FE94ACEEF71F0 (opens in new tab)

PubPeer CommentSource: PubPeer.com — a platform for post-publication peer review

Commenter: Psilocladia obliquataDate: 1 May 2021

A quick view shows inconsistencies as you can't loose probands to follow-up and report a change from baseline. [Image: file illustrating possible data inconsistencies] Is anybody willing to look at the distribution of the last numbers?

Thread: https://pubpeer.com/publications/925CE537207BD1E90FE94ACEEF71F0 (opens in new tab)

Q1.3 — Do other studies by the research team highlight causes for concern?

Automated Assessment:Assessment produced by the automated systemYes
Human Assessment:Assessment by a domain expert reviewer, informed by AI resultsYes

Rationale: No rationale provided

Supporting Evidence (62)

Retraction NoticeSource: Retraction Watch database

The Effect of Zinc Supplementation on Expressed Levels of Peroxisome Proliferator-Activated Receptor Gamma and Glucose Transporter Type 1 Genes in Newborns of Women with Gestational Diabetes Mellitus

10.1007/s12011-016-0788-y (opens in new tab)
Journal: Biological Trace Element ResearchPublisher: SpringerDate: 28 Feb 2021

RetractionWatch ID:Record identifier in the Retraction Watch database 28454

Rationale: Concerns/Issues About Data;Investigation by Company/Institution;Updated to Retraction

About Authors: Mehri Jamilian, Mansooreh Samimi, Esmat Aghadavod

Retraction NoticeSource: Retraction Watch database

Effects of Selenium Supplementation on Gene Expression Levels of Inflammatory Cytokines and Vascular Endothelial Growth Factor in Patients with Gestational Diabetes

10.1007/s12011-017-1045-8 (opens in new tab)
Journal: Biological Trace Element ResearchPublisher: SpringerDate: 28 Feb 2021

RetractionWatch ID:Record identifier in the Retraction Watch database 28465

Rationale: Concerns/Issues About Data;Investigation by Company/Institution

About Authors: Mehri Jamilian, Mansooreh Samimi, Esmat Aghadavod, Faraneh Afshar Ebrahimi

Retraction NoticeSource: Retraction Watch database

The Effect of Zinc Supplementation on Expressed Levels of Peroxisome Proliferator-Activated Receptor Gamma and Glucose Transporter Type 1 Genes in Newborns of Women with Gestational Diabetes Mellitus

10.1007/s12011-022-03501-2 (opens in new tab)
Journal: Biological Trace Element ResearchPublisher: SpringerDate: 24 Nov 2022

RetractionWatch ID:Record identifier in the Retraction Watch database 40895

Rationale: Concerns/Issues About Data;Concerns/Issues About Image;Concerns/Issues about Referencing/Attributions;Duplication of/in Article;Investigation by Company/Institution;Unreliable Results and/or Conclusions;Upgrade/Update of Prior Notice(s)

About Authors: Mehri Jamilian, Mansooreh Samimi, Esmat Aghadavod

Q2.2 — Are there concerns relating to the timing or absence of study registration?

Automated Assessment:Assessment produced by the automated systemYes
Human Assessment:Assessment by a domain expert reviewer, informed by AI resultsYes

Rationale: No rationale provided

Supporting Evidence (2)

Clinical Trial RegistrationSource: Clinical trial registry (e.g. ClinicalTrials.gov, ISRCTN)

Registration ID: IRCT201309275623N10

Registry: IRCT

Registry Link: https://trialsearch.who.int/Trial2.aspx?TrialID=IRCT201309275623N10 (opens in new tab)

Registration Date: 7 Oct 2013

Prospective:Whether the trial was registered before participant recruitment began No

Assessment Rationale:How INSPECT-AI determined the prospective registration status by comparing dates Comparison performed at month level. Registration: 2013-10, LLM Recruitment Start: 2013-09. Deemed retrospective at month level.

Study Design EvidenceDates and timelines extracted by INSPECT-AI from the publication text

Recruitment Start: 09-2013

Recruitment Start Rationale:INSPECT-AI's reasoning for how it identified the recruitment start date Methods: 'This randomized double-blind placebo controlled clinical trial was performed in Kashan, Iran, during September 2013 to December 2013.'

Recruitment End: 12-2013

Recruitment End Rationale:INSPECT-AI's reasoning for how it identified the recruitment end date Methods: 'This randomized double-blind placebo controlled clinical trial was performed in Kashan, Iran, during September 2013 to December 2013.'

Study End: N/A

Study End Rationale:INSPECT-AI's reasoning for how it identified the study end date No explicit study completion date found.

Overall — What is the overall integrity assessment of the study?

Automated Assessment:Assessment produced by the automated systemN/A
Human Assessment:Assessment by a domain expert reviewer, informed by AI resultsSerious concerns

Rationale: No rationale provided