Single oral dose of vitamin D3 supplementation prior to in vitro fertilization and embryo transfer in normal weight women: the SUNDRO randomized controlled trial
Assessed by RV013 · Clinical Chair in Health Services Research
Assessed on 2 Mar 2026
OverallReviewer's overall integrity assessment, derived from all research questions Serious concerns
DOI 10.1016/j.ajog.2021.04.234 (opens in new tab)
Resource ripekg:research-integrity-assessment/RIPEA212731D631747726
5 Research Questions · 7 Evidence Items
Q1.1 — Does the study have an associated retraction?
Rationale: No retraction found
Q1.2 — Does the study have an associated expression of concern or other relevant post-publication notice?
Rationale: No rationale provided
Q1.3 — Do other studies by the research team highlight causes for concern?
Rationale: Multiple concerns
Supporting Evidence (5)
Retraction NoticeSource: Retraction Watch database
Attractiveness of women with rectovaginal endometriosis: a case-control study
10.1016/j.fertnstert.2020.09.001 (opens in new tab)RetractionWatch ID:Record identifier in the Retraction Watch database 24180
Rationale: Objections by Third Party
About Author: Edgardo Somigliana
Retraction NoticeSource: Retraction Watch database
Randomized, double blind placebo-controlled trial: effects of Myo-inositol on ovarian function and metabolic factors in women with PCOS
10.26355/eurrev_202309_33752 (opens in new tab)RetractionWatch ID:Record identifier in the Retraction Watch database 47831
Rationale: Concerns/Issues About Authorship/Affiliation;Duplication of/in Article;Investigation by Third Party;Lack of Approval from Author
About Author: Enrico Papaleo
Retraction NoticeSource: Retraction Watch database
Psychological assessment of the effects of treatment with phytoestrogens on postmenopausal women: a randomized, double-blind, crossover, placebo-controlled study
10.1016/j.fertnstert.2024.12.003 (opens in new tab)RetractionWatch ID:Record identifier in the Retraction Watch database 60883
Rationale: Concerns/Issues About Data;Duplication of Data;Euphemisms for Duplication;Investigation by Journal/Publisher;Investigation by Third Party
About Author: Enrico Papaleo
Q2.2 — Are there concerns relating to the timing or absence of study registration?
Rationale: Eudract number registered 2015
Supporting Evidence (2)
Clinical Trial RegistrationSource: Clinical trial registry (e.g. ClinicalTrials.gov, ISRCTN)
Registration ID: 2015-004233-27
Registry: EU CTR
Registry Link: https://trialsearch.who.int/Trial2.aspx?TrialID=2015-004233-27 (opens in new tab)
Prospective:Whether the trial was registered before participant recruitment began No
Assessment Rationale:How INSPECT-AI determined the prospective registration status by comparing dates Registry registration date (study_first_submit_qc_date) is missing or empty.
Study Design EvidenceDates and timelines extracted by INSPECT-AI from the publication text
Recruitment Start: 10-10-2016
Recruitment Start Rationale:INSPECT-AI's reasoning for how it identified the recruitment start date Materials and Methods: 'the date of initial participant enrollment was October 10, 2016.'
Recruitment End: 01-2019
Recruitment End Rationale:INSPECT-AI's reasoning for how it identified the recruitment end date Materials and Methods: 'Women undergoing IVF... between October 2016 and January 2019 were considered for study entry.' This indicates that recruitment finished in January 2019.
Study End: 08-2020
Study End Rationale:INSPECT-AI's reasoning for how it identified the study end date Outcome measures: 'Recruitment was stopped once the scheduled sample size was reached. Follow-up was prolonged up to the end of August 2020.'
Overall — What is the overall integrity assessment of the study?
Rationale: Previous retractions for two authors.