Effect of low-dose selenium on thyroid autoimmunity and thyroid function in UK pregnant women with mild-to-moderate iodine deficiency
Assessed by RV009 · Systematic reviewer
Assessed on 12 Nov 2025
OverallReviewer's overall integrity assessment, derived from all research questions Some concerns
DOI 10.1007/s00394-014-0822-9 (opens in new tab)
Resource ripekg:research-integrity-assessment/RIPEA1718ED934D2F66F4
5 Research Questions · 2 Evidence Items
Q1.1 — Does the study have an associated retraction?
Rationale: No rationale provided
Q1.2 — Does the study have an associated expression of concern or other relevant post-publication notice?
Rationale: I agree
Q1.3 — Do other studies by the research team highlight causes for concern?
Rationale: I agree
Q2.2 — Are there concerns relating to the timing or absence of study registration?
Rationale: No rationale provided
Supporting Evidence (2)
Clinical Trial RegistrationSource: Clinical trial registry (e.g. ClinicalTrials.gov, ISRCTN)
Registration ID: ISRCTN37927591
Registry: ISRCTN
Registry Link: https://trialsearch.who.int/Trial2.aspx?TrialID=ISRCTN37927591 (opens in new tab)
Registration Date: 5 Oct 2013
Prospective:Whether the trial was registered before participant recruitment began No
Assessment Rationale:How INSPECT-AI determined the prospective registration status by comparing dates LLM-extracted recruitment start date (normalized_date) is missing or empty.
Study Design EvidenceDates and timelines extracted by INSPECT-AI from the publication text
Recruitment Start: N/A
Recruitment Start Rationale:INSPECT-AI's reasoning for how it identified the recruitment start date No recruitment start date found in the text.
Recruitment End: N/A
Recruitment End Rationale:INSPECT-AI's reasoning for how it identified the recruitment end date No recruitment end date found in the text.
Study End: N/A
Study End Rationale:INSPECT-AI's reasoning for how it identified the study end date No study end date found in the text.
Overall — What is the overall integrity assessment of the study?
Rationale: There were actually no concerns identified, but one item was marked as ‘unclear’ regarding the registration issue. Given that, I felt it was neither ‘no concerns’ nor ‘serious concerns,’ so I selected ‘some concerns’ as it was the only available option.