Cost-effectiveness of high flow nasal cannula therapy versus continuous positive airway pressure for non-invasive respiratory support in paediatric critical care
Assessed by RV008 · PhD Candidate
Assessed on 16 Nov 2025
OverallReviewer's overall integrity assessment, derived from all research questions No concerns
DOI 10.1186/s13054-024-05148-y (opens in new tab)
Resource ripekg:research-integrity-assessment/RIPEA0E6BB9EA03F91869
5 Research Questions · 2 Evidence Items
Q1.1 — Does the study have an associated retraction?
Rationale: No rationale provided
Q1.2 — Does the study have an associated expression of concern or other relevant post-publication notice?
Rationale: No rationale provided
Q1.3 — Do other studies by the research team highlight causes for concern?
Rationale: No rationale provided
Q2.2 — Are there concerns relating to the timing or absence of study registration?
Rationale: No rationale provided
Supporting Evidence (2)
Clinical Trial RegistrationSource: Clinical trial registry (e.g. ClinicalTrials.gov, ISRCTN)
Registration ID: ISRCTN60048867
Registry: ISRCTN
Registry Link: https://trialsearch.who.int/Trial2.aspx?TrialID=ISRCTN60048867 (opens in new tab)
Registration Date: 19/06/2019
Prospective:Whether the trial was registered before participant recruitment began Yes
Assessment Rationale:How INSPECT-AI determined the prospective registration status by comparing dates Comparison performed at month level. Registration: 2019-06, LLM Recruitment Start: 2019-08. Deemed prospective at month level.
Study Design EvidenceDates and timelines extracted by INSPECT-AI from the publication text
Recruitment Start: 08-2019
Recruitment Start Rationale:INSPECT-AI's reasoning for how it identified the recruitment start date Methods: 'Each RCT (step-up and step-down) recruited 600 patients between August 2019 and November 2021'; no specific day found.
Recruitment End: 11-2021
Recruitment End Rationale:INSPECT-AI's reasoning for how it identified the recruitment end date Methods: 'Each RCT (step-up and step-down) recruited 600 patients between August 2019 and November 2021'; no specific day found.
Study End: 18-03-2022
Study End Rationale:INSPECT-AI's reasoning for how it identified the study end date Methods: 'with last follow-up completed on 18 March 2022'.
Overall — What is the overall integrity assessment of the study?
Rationale: No rationale provided