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Evaluating Primary Treatment for People with Advanced Glaucoma

Assessed by RV005 · Statistician

Assessed on 11 Nov 2025

OverallReviewer's overall integrity assessment, derived from all research questions No concerns

DOI 10.1016/j.ophtha.2024.01.007 (opens in new tab)

Resource ripekg:research-integrity-assessment/RIPEA07C7CD7A66B0506A

5 Research Questions · 2 Evidence Items

Q1.1 — Does the study have an associated retraction?

Automated Assessment:Assessment produced by the automated systemNo
Human Assessment:Assessment by a domain expert reviewer, informed by AI resultsNo

Rationale: Agree

Q1.2 — Does the study have an associated expression of concern or other relevant post-publication notice?

Automated Assessment:Assessment produced by the automated systemNo
Human Assessment:Assessment by a domain expert reviewer, informed by AI resultsNo

Rationale: Agree

Q1.3 — Do other studies by the research team highlight causes for concern?

Automated Assessment:Assessment produced by the automated systemNo
Human Assessment:Assessment by a domain expert reviewer, informed by AI resultsNo

Rationale: Agree

Q2.2 — Are there concerns relating to the timing or absence of study registration?

Automated Assessment:Assessment produced by the automated systemNo
Human Assessment:Assessment by a domain expert reviewer, informed by AI resultsNo

Rationale: Agree

Supporting Evidence (2)

Clinical Trial RegistrationSource: Clinical trial registry (e.g. ClinicalTrials.gov, ISRCTN)

Registration ID: ISRCTN56878850

Registry: ISRCTN

Registry Link: https://trialsearch.who.int/Trial2.aspx?TrialID=ISRCTN56878850 (opens in new tab)

Registration Date: 14/01/2014

Prospective:Whether the trial was registered before participant recruitment began Yes

Assessment Rationale:How INSPECT-AI determined the prospective registration status by comparing dates Registration date is on or before LLM recruitment start date.

Study Design EvidenceDates and timelines extracted by INSPECT-AI from the publication text

Recruitment Start: 03-06-2014

Recruitment Start Rationale:INSPECT-AI's reasoning for how it identified the recruitment start date Participants were recruited from June 3, 2014.

Recruitment End: 31-05-2017

Recruitment End Rationale:INSPECT-AI's reasoning for how it identified the recruitment end date Participants were recruited until May 31, 2017.

Study End: N/A

Study End Rationale:INSPECT-AI's reasoning for how it identified the study end date No explicit study end date found; only the follow-up duration (5 years) is mentioned.

Overall — What is the overall integrity assessment of the study?

Automated Assessment:Assessment produced by the automated systemN/A
Human Assessment:Assessment by a domain expert reviewer, informed by AI resultsNo concerns

Rationale: Agree