The Effects of Vitamin D Supplementation on Metabolic Status of Patients with Polycystic Ovary Syndrome: A Randomized, Double-Blind, Placebo-Controlled Trial
Assessed by RV004 · Research Assistant
Assessed on 3 Nov 2025
OverallReviewer's overall integrity assessment, derived from all research questions Serious concerns
DOI 10.1055/s-0043-107242 (opens in new tab)
Resource ripekg:research-integrity-assessment/RIPEA068C16C1B806E52A
5 Research Questions · 28 Evidence Items
Q1.1 — Does the study have an associated retraction?
Rationale: No rationale provided
Supporting Evidence (1)
Retraction NoticeSource: Retraction Watch database
Effects of vitamin D supplementation on glucose metabolism, lipid concentrations, inflammation, and oxidative stress in gestational diabetes: a double-blind randomized controlled clinical trial
10.1093/ajcn/nqab071 (opens in new tab)RetractionWatch ID:Record identifier in the Retraction Watch database 28312
Rationale: Concerns/Issues About Data;Upgrade/Update of Prior Notice(s)
About Authors: Mansooreh Samimi, Teibeh Hashemi, Maryam Karamali, Ahmad Esmaillzadeh
Q1.2 — Does the study have an associated expression of concern or other relevant post-publication notice?
Rationale: No rationale provided
Supporting Evidence (1)
PubPeer ThreadSource: PubPeer.com — post-publication peer review comments
https://pubpeer.com/publications/778B47FAAF79492CFD327C4652FC2E (opens in new tab)PubPeer CommentSource: PubPeer.com — a platform for post-publication peer review
There are many concerns about the integrity of 172 publications by this research group, including this one. Some of the concerns are published 1. Anaesthesia 2020;75:1683–92, see Supplementary data. This paper is A103 2. Account Res 2020;28:149-61. 3. J Clin Epidemiol 2021;131:22-29. Journals and publishers were notified of these concerns in July 2019. 23 publications have an expression of concern. To our knowledge there has been no public response about any of the concerns. We think these publications are unreliable
Thread: https://pubpeer.com/publications/778B47FAAF79492CFD327C4652FC2E (opens in new tab)
Q1.3 — Do other studies by the research team highlight causes for concern?
Rationale: No rationale provided
Supporting Evidence (24)
Retraction NoticeSource: Retraction Watch database
Magnesium-Zinc-Calcium-Vitamin D Co-supplementation Improves Hormonal Profiles, Biomarkers of Inflammation and Oxidative Stress in Women with Polycystic Ovary Syndrome: a Randomized, Double-Blind, Placebo-Controlled Trial
10.1007/s12011-022-03465-3 (opens in new tab)RetractionWatch ID:Record identifier in the Retraction Watch database 40898
Rationale: Concerns/Issues About Data;Concerns/Issues About Image;Concerns/Issues about Referencing/Attributions;Duplication of/in Article;Error in Data;Investigation by Company/Institution;Unreliable Results and/or Conclusions;Upgrade/Update of Prior Notice(s)
About Authors: Mehri Jamilian, Maryam Maktabi
Retraction NoticeSource: Retraction Watch database
Probiotic supplementation and the effects on weight loss, glycaemia and lipid profiles in women with polycystic ovary syndrome: a randomized, double-blind, placebo-controlled trial
10.1080/14647273.2024.2373595 (opens in new tab)RetractionWatch ID:Record identifier in the Retraction Watch database 54767
Rationale: Concerns/Issues About Data;Concerns/Issues about Results and/or Conclusions;Concerns/Issues about Referencing/Attributions;Investigation by Journal/Publisher;Investigation by Third Party;Objections by Author(s);Unreliable Results and/or Conclusions;Upgrade/Update of Prior Notice(s)
About Authors: Mohsen Taghizadeh, Zatollah Asemi, Mehri Jamilian, Maryam Tajabadi-Ebrahimi, Maryam Karamali, Mohammad Memarzadeh
Retraction NoticeSource: Retraction Watch database
Effect of daily consumption of probiotic yoghurt on lipid profiles in pregnant women: a randomized controlled clinical trial
10.1080/14767058.2024.2364976 (opens in new tab)RetractionWatch ID:Record identifier in the Retraction Watch database 67044
Rationale: Concerns/Issues About Data;Concerns/Issues about Results and/or Conclusions;Investigation by Journal/Publisher;Investigation by Third Party;Objections by Author(s);Unreliable Results and/or Conclusions;Upgrade/Update of Prior Notice(s)
About Authors: Zatollah Asemi, Ahmad Esmaillzadeh
Q2.2 — Are there concerns relating to the timing or absence of study registration?
Rationale: No rationale provided
Supporting Evidence (2)
Clinical Trial RegistrationSource: Clinical trial registry (e.g. ClinicalTrials.gov, ISRCTN)
No trial registration found
Assessment Rationale:How INSPECT-AI determined the prospective registration status by comparing dates Registry registration date (study_first_submit_qc_date) is missing or empty.
Study Design EvidenceDates and timelines extracted by INSPECT-AI from the publication text
Recruitment Start: 04-2016
Recruitment Start Rationale:INSPECT-AI's reasoning for how it identified the recruitment start date Methods: 'between April 2016 and June 2016 were included'; using start of recruitment period.
Recruitment End: 06-2016
Recruitment End Rationale:INSPECT-AI's reasoning for how it identified the recruitment end date Methods: 'between April 2016 and June 2016 were included'; using end of recruitment period.
Study End: N/A
Study End Rationale:INSPECT-AI's reasoning for how it identified the study end date No explicit study completion date found.
Overall — What is the overall integrity assessment of the study?
Rationale: A reference for this study has been retracted. Normally, we need to assess whether this retraction consistently affects the results of the study. However, the fact that the authors have a total of three retracted papers, along with the absence of this trial in a registry, raises serious concerns.